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The NovaSeq Xp workflow enables individual lane loading on the same flow cell. Hence the multiplexing capacity can be expanded 2 times using the NovaSeq XP 2-Lane Kit or 4 times with the NovaSeq XP 4-Lane Kit. Hence, it is possible load up to 4 physically separated 384-plex UDI-indexed libraries per flow cell. For more information about the Xp Workflow, please refer to the NovaSeq™ Xp workflow Technical Note, The NovaSeq™ Xp workflow explanatory video, or contact Illumina Support.