The main difference between CORALL RTM and RTL is the reverse transcription chemistry, which influences the insert size of the final libraries.
The RTM Chemistry is comparable to the CORALL V1 standard protocol and is therefore perfectly suited for expression profiling and for low-quality RNA input, including FFPE samples.
When this chemistry is used, the expected average size of the library is approximately 350 bp.
The RTM chemistry enables time- and cost-effective single-read sequencing for expression profiling (recommended length: SR50 - 150). Paired-end sequencing is also compatible (recommended length: PE50-75).
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