Lexogen Online FAQs

Why is the percentage of rRNA reads higher when globin is depleted?

Owned by Matteo Carina (Unlicensed)
Last updated: Nov 15, 2021 by Stephanie Bannister
1 min read

This increase is expected due to the fact that 35 – 75 % of mRNA (specifically, globin mRNA) is removed. In absolute numbers, the rRNA stays the same but makes up a larger fraction of reads due to the decrease in non-rRNA fraction.

Have feedback for us or need more information? Send us a request or write to us at support@lexogen.com.