No, it depends on what kind of targeted sequencing you intend to do. The modules are compatible with the QuantSeq with UDI V2 kits (Cat. No. 191 - 196) and with the QuantSeq FWD V1 kits (Cat. No. 015, 113 – 115, 129 – 131).
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Using both the QuantSeq-Flex First and Second Strand Synthesis Modules allows you to generate fully-targeted libraries to identify known targets at specified sequence regions. This is the ideal approach when seeking to replace multiplex qPCR with an Amplicon-based targeted RNA-Seq assay.
NOTE: The second strand synthesis reaction requires annealing temperatures of >45 °C. In case you need to use lower temperatures, please contact support@lexogen.com.