Does RiboCop for Yeast efficiently deplete rRNA from low quality RNA?

Yes, RiboCop for Yeast reduces rRNA reads in low quality RNA (RIN ~2) to 2 - 5% over a broad range of input amounts (10 - 1,000 ng).

Please note that depletion rates may vary depending on the quality of the RNA and purity of the sample. Contaminants, such as salts, metal ions, and organic solvents, may have a negative impact on the efficiency of the protocol.