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Should I perform a DNase treatment before QuantSeq FFPE?

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Created by Lauren Sheehan, last modified by Branislav.Lilic on Apr 09, 2024

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As the risk of gDNA contamination is higher due to the degradation of RNA in FFPE samples, it is recommended to perform a DNase treatment prior to library prep.

Two options for DNase ~~treating~~ treatment of FFPE samples are:

DNA Removal Add-on Module (Cat. No. 235) or
SPLIT One-Step FFPE RNA Extraction Kit (Cat. No. 236)

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